Van de Ven Double Halts Everton's Unbeaten Streak at New Home Ground
The Dutch defender became the first defender to score twice in a Premier League game for Tottenham since the Belgian defender in March 2013.
Match summary
The Spurs defender heads home two times in opening period
Everton's Jake O'Brien has goal ruled after video check
Senegalese midfielder scores third in dying moments
This loss is Everton's first at their new ground
The Tottenham defender scored twice as Spurs prolonged their winning streak on the road in the top division and delivered Everton their initial loss at their new home.
Everton were unbeaten in their last five matches at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after more than a century at the conclusion of last season.
But Tottenham's leader the Dutchman struck twice from corners in the opening 45 minutes to put their impressive record at jeopardy, and they were unable to turn it around before the midfielder - set up by former Toffees attacker the Brazilian - headed home a third to seal the victory.
The Everton defender believed he had levelled the tally five minutes after the defender's opener, directing a powerful header past Guglielmo Vicario from an Everton corner.
Beto, meanwhile, missed a handful of chances, while the Italian goalkeeper made a series of fine stops to guarantee Tottenham went five away games without defeat in the Premier League.
But the video assistant referee stepped in, instructing the match official to review the score on the screen and the referee decided that Jack Grealish and the attacker were in offside positions and had impeded with the Spurs keeper.
This victory moves the manager's team into third place in the division, a handful of points off local foes and leaders the Gunners.
The Merseyside club remain 14th and sit six points ahead of the drop zone.
Tottenham analysis: The defender excels in role at each end of pitch
After a uninspiring midweek performance in the Champions League against the French side, where they managed a mere attempts on target, the manager opted for the French striker up front instead of former Toffees player the Brazilian.
The summer signing was failed to influence the game before being replaced for the substitute after 60 minutes on the field, but it turns out he proved unnecessary in the end.
Centre-back Van de Ven converted into an attacking force to be reckoned with.
Tottenham's first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur heading the ball back across the six-yard box for an free the defender to head home.
And the captain - filling in as skipper in the Argentine's absence - notched his second in added time as he rose above the England keeper to nod in.
The Dutchman was just as impressive in defensive duties, partnering effectively with his defensive colleague as the pair handled superbly with the numerous deliveries sent their way by Everton.
Toffees breakdown: Toffees missing striker's instinct
The club's new home had been a fortress, but it seems the freshness may have faded somewhat and supporters flocked to the exits after the midfielder's final goal for Spurs.
The end in the team's winning streak at home won't be a major worry for the manager, but their attacking woes will be.
The forward and the other striker - the Toffees' pair of established strikers - had netted just a single goal between them before the weekend's match.
And they were unable to add to that poor record on a damp and dreary evening on Merseyside.
The striker's performance was summed up when he chose to overhead kick a clear chance from near the goal, even with having space and opportunity to readjust for a more conventional shot that would have challenged the keeper.
The substitute, as well, failed to make an impact after coming on for the starter in the second half.
It wasn't for a lack of chance. The majority of the home side's offensive moves came through Grealish and the forward, who relentlessly whipped dangerous crosses into the Tottenham penalty area.
Upcoming fixtures for both teams?
Everton: Moyes' men travel to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Tottenham: The London club travel to Newcastle's ground on Wednesday, 29 October for their next round League Cup match against the Magpies.